Fourteen tournaments since a 1970 debut have produced five quarter-finals, all of them since 2004. The 2006 side of Pascal Feindouno and Kaba Diawara won all three group games in Egypt before losing a 3–2 quarter-final to Senegal; in 2012 Guinea beat Botswana 6–1, still their biggest win at the finals, and yet did not get out of the group.
Côte d’Ivoire 2023 brought the fifth quarter-final, secured by Mohamed Bayo’s winner eight minutes into stoppage time against Equatorial Guinea; DR Congo won the quarter-final 3–1. Guinea then missed Morocco 2025, finishing third behind DR Congo and Tanzania despite six qualifying goals from Serhou Guirassy.
Paulo Duarte’s squad faces a narrower road than most. Kenya, co-hosts of the 2027 finals, are in Group D and have qualified automatically, so only the best-placed of Guinea, South Africa and Eritrea will join them. The campaign starts against South Africa in Johannesburg on 26 September, and Kenya visit Conakry on 1 October.